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Overview

Date Established 04/2022
Founder Mark Menning
Headquarters None
Industries
Health & Wellness
Science & Research
Beauty
Tech
Website https://www.marklosangeles.com
Social

About

MARK Los Angeles is a skincare company founded by Mark Menning PhD, a pharmaceutical scientist, and Dee Khalsa, a spa and wellness expert. They focus on creating plant-based skincare solutions that are free of harsh chemicals, leveraging Menning's expertise in pharmaceutical precision. Their products are clinically tested, cruelty-free, and designed to provide effective treatment while maintaining high ethical and sustainable standards. The company's mission is to revolutionize skincare through the use of nature's medicinal chemistry.

Founding Story

MARK Los Angeles was founded by pharmaceutical scientist Mark Menning, PhD, whose lifelong interest in flavonoids led him to a breakthrough in skincare science. While flavonoids are well known for their anti-inflammatory and antioxidant benefits, Dr. Menning recognized a major limitation: poor oral bioavailability and ineffective delivery in traditional skincare formulations.

Determined to overcome these barriers, he developed XDF (transdermal flavosomes)—a novel delivery technology that enables compounds to penetrate the skin barrier and reach their therapeutic targets. This innovation became the foundation of MARK Los Angeles, a brand that combines clinical precision with the power of plant science to deliver real, measurable results.

MARK Los Angeles is driven by the belief that science and nature are most powerful when working together, and that skincare should be both highly effective and expertly formulated.

Team Bios

Mark Menning, PhD is a pharmaceutical scientist and the founder of MARK Los Angeles, a California-based skincare brand pioneering the use of flavonoids and advanced transdermal delivery to address cold sores, acne, and inflammation. With a PhD in Chemical Engineering and a track record that includes formulating FDA-approved antiviral therapies like Truvada and Atripla, Mark brings a rare blend of clinical expertise and entrepreneurial vision to the beauty and wellness space.


His first venture, Nucleo Life Sciences, provided laboratory services focused on translational pharmaceutics and novel delivery systems, supporting clinical-stage programs for small, mid-sized, and large pharmaceutical companies. At the core of the brand is XDF™ (Transdermal Flavosomes), a proprietary system designed to solve the long-standing bioavailability issues of flavonoids by enabling them to penetrate the skin effectively.


This technology drives a growing portfolio of performance-first products, including the Lip Rescue Serum and Lip Health Balm—a new standard in cold sore care—as well as the E.Q. Clear Skin collection, a clinically tested line formulated with flavonoids to calm inflammation and visibly improve blemish-prone skin.


Mark is committed to bridging science and skincare, translating plant compounds into clinically validated actives with real-world efficacy and pharmaceutical-grade precision.

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